Vaccine against nicotine dependence - A promising strategy

Smoking is one of the catastrophic health conditions that are taking a toll on the health of many individuals including the younger generation. And, the inception of a vaccine against nicotine addiction is a step forward in this regard, which is a pr

Fontana, CA (prHWY.com) July 4, 2012 - 4 July 2012, USA (Realpharmacyrx.us): Researchers on an NIH-funded project have developed a vaccine targeting nicotine addiction, which is found to be the major cause of various clinical conditions resulting in death of one in every 5 Americans.
The vaccine has proven to be successful in treating this debilitating obsession in mice and has paved the way for development of potential therapeutic approaches for curing many other detrimental addictions.
It is a known fact that despite been taking various measures for prevention of smoking by the government, around 20% Americans still prefer smoking. The various warnings related to the perils of smoking and its allied health effects that include emphysema, lung cancer and COPD, almost 75% of individuals who quit smoking revert back to their normal habit within a time frame of six months.
All these health hazards can be checked out with the aid of a single dose of this vaccine that provides lifelong protection against nicotine habit.

The vaccine is found to act by stimulating the liver cells to produce antibodies on a continuous basis such that as soon as they encounter nicotine molecules in the blood; they get absorbed quickly, thereby preventing the nicotine molecules from entering the brain or heart areas. And, this blockage inhibits the individuals from enjoying the pleasures of smoking.
Dr. Ronald Crystal, chairman of Weill Cornell Medical College and professor of Genetic Medicine said that the main reason for the potent activity of these nicotine antibodies is attributed to the fact that the vaccine prompts the body to produce its own antibodies making the approach more efficient and reliable as compared to previous techniques which employed the antibodies directly into the body.
The current vaccine is found to possess no harmful health effects but, testing is still in its developmental stages before a full-fledged human trial will be carried out, which is more likely to be taking another 24 months for conducting it in humans.
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